Product Overview
GF-1 LR3 is a research peptide analog of human insulin-like growth factor 1 (IGF-1) containing a 13–amino acid N-terminal extension that enhances stability and receptor binding. It interacts with the IGF-1 receptor to activate PI3K/Akt and MAPK/ERK pathways involved in cellular growth, differentiation, and metabolic regulation. IGF-1 LR3 is used in experimental models to study peptide-mediated anabolic signaling, receptor kinetics, and tissue remodeling mechanisms.
IGF1-LR3 (insulin-like growth factor-1 long arginine-3) is a synthetic analog of insulin-like growth factor-1 engineered for use in laboratory research. Structural modifications include N-terminal amino acid extension and substitution of glutamic acid with arginine at position three, resulting in reduced affinity for IGF-binding proteins. These modifications extend molecular persistence in experimental systems, enabling prolonged interaction with IGF-associated receptors in controlled in-vitro and in-vivo animal models. Preclinical research utilizes IGF1-LR3 as a tool compound to investigate growth factor-mediated signaling, cellular proliferation pathways, differentiation programs, and metabolic signaling cascades. All discussion herein is limited to experimental research contexts and does not imply applied, therapeutic, or physiological use.
Storage & Handling
Molecular Information
Quality Assurance
Every batch undergoes comprehensive third-party testing
HPLC Analysis
High-Performance Liquid Chromatography confirms peptide purity and identity
Mass Spectrometry
Molecular weight verification through advanced mass spec analysis
Endotoxin Testing
LAL assay confirms endotoxin levels meet strict specifications